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«An interesting thing about piracetam use is that it doesn’t do very much by itself. The standard advice is to take a choline supplement with the piracetam. A gram of straight choline still boosts piracetam’s effects from subtle or placebo, to noticeable & measurable.» - http://www.gwern.net/Drug heuristics?2
The whole article is quite interesting. It's a research on "Algernon's law", which reads: «Any simple major enhancement to human intelligence is a net evolutionary disadvantage.» ‎- 9000